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Stratum lucidum of hippocampus : ウィキペディア英語版 | Stratum lucidum of hippocampus
:''For the layer of the skin, see stratum lucidum''.'' The stratum lucidum of the hippocampus is also a layer of the hippocampus between the stratum pyramidale and the stratum radiatum. It is the tract of the mossy fiber projections, both inhibitory and excitatory from the granule cells of the dentate gyrus. One mossy fiber may make up to 37 connections to a single pyramidal cell, and innervate around 12 pyramidal cells on top of that. Any given pyramidal cell in the stratum lucidum may get input from as many as 50 granule cells. ==Location==
The stratum lucidum is located within the CA3 region of the hippocampus distally to the dentate gyrus and proximally to the CA2 region. For further information on the regions, see Hippocampus anatomy. It is composed of a densely packed bundle of mossy fibers (unmyelinated) and spiny and aspiny interneurons that lie immediately above the CA3 pyramidal cell layer in the hippocampus, and immediately below the stratum radiatum. Most mossy fiber axons are perpendicular to the CA3 pyramidal region where they project and synapse to either the CA3 pyramidal cells or the stratum oriens below the pyramidal region. The interneurons of the stratum lucidum are generally found to be local circuit neurons remaining within the CA3 region. A majority of the interneuron axons remain within the stratum lucidum but some also extend to the stratum radiatum and stratum lacunosum-molecular above the radiatum as well as to the CA1 and hilur regions.
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